By Harry G. Brittain
Even though the authentic compendia outline a drug substance as to identification, purity, power, and caliber, they often don't offer different actual or chemical information, nor do they record tools of synthesis or pathways of actual or organic degradation and metabolism. Such info is scattered in the course of the medical literature and the documents of pharmaceutical laboratories. Edited by way of the affiliate Director of Analytical examine and improvement for the AmericanAssociation of Pharmaceutical Scientists, Analytical Profiles of Drug ingredients and Excipients brings this data jointly into one resource. The scope of the sequence has lately been improved to incorporate profiles of excipient fabrics.
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Extra info for Analytical Profiles of Drug Substances and Excipients, Volume 23 (Analytical Profiles of Drug Substances, Excipients, and Related Methodology)
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Czeh, Acta Pharm. , 49,68 (1979); Chem. , 90,210188 (1979). 82. British Pharmacopoeia 1993, Her Majesty's Stationery Office, London, A125 (1993). 83. P. Sin& N. K. Roy and SKMandal, Indian J. Exp. , 22,39 (1984). 84. E. M. Everett, Anal. , 21,670 (1949). 85. United States Pharmacopoeia XX , USP Convention Inc. , 1283 (1980). 86. P. E. V. Prasad, Talantu, 33, 164 (1986); Chem. , 105, 12199 (1986). BIRD 48 87. M. G. W. Ibrahim, Indian J. Pharnt. , 47, 174 (1985); Cheni. , 105,66532 (1986). 88. F.
Pla-Delfina, Biopharm. , 13, 39 (1992); Chem. A h . , 116, 120341 (1992). DILTIAZEM HYDROCHLORIDE David J. Mazzo,' Cynthia L. O W : and J. A. ANALYTICAL PROFILES OF DRUG SUBSTANCES 53 AND EXCIPIENTS-VOLUME 23 CopyrightQ 1994 by Academic Press, Inc. All rights of reproduction in any form reserved. DAVID J. MAZZO ET AL. DlLTlAZEM HYDROCHLORIDE 1. 1. 2. History 2. 1. 2. 3. Appearance, Odor and Taste 3. SYNTHESIS 4. 1. 2. 1. 2. 3. 4. 5. 6. 7. 1. 2. 3. 4. 5. 8. 9. 1. 2. 3. pH 5. 1. l. 2. 3. 2. 1. 2.
Analytical Profiles of Drug Substances and Excipients, Volume 23 (Analytical Profiles of Drug Substances, Excipients, and Related Methodology) by Harry G. Brittain